Notational Velocity is a mouseless application for storing and retrieving notes.
With Notational Velocity, searching for notes is not a separate action; rather, it is the primary interface. Searching encompasses all notes content and occurs instantly with each key pressed.
All content created with Notational Velocity is compressed and encrypted (enabled optionally) before it is recorded to disk. Additionally, there is no manual "saving"; all modifications take effect immediately.
Notational Velocity's window was designed for keyboard input above all else, and thus has no buttons.
You can synchronize your notes with Simplenote, or via files in Dropbox with PlainText, Elements, iA Writer, and other iOS apps.