YUMI exFAT is described as 'The YUMI exFAT (Your Universal Multiboot Installer) media creation tool can be used to automatically create an exFAT bootable USB flash drive containing multiple operating systems, antivirus utilities, disc cloning, diagnostic tools, and more' and is a very popular bootable usb creator in the os & utilities category. There are more than 50 alternatives to YUMI exFAT for a variety of platforms, including Windows, Linux, Mac, Flathub and Flatpak apps. The best YUMI exFAT alternative is Rufus, which is both free and Open Source. Other great apps like YUMI exFAT are Ventoy, balenaEtcher, UNetbootin and Universal USB Installer.
Rufus alone doesn't, but used with the ISO by Multisystem allow to multiboot from an USB device.