The best open source alternative to Cubase is LMMS, which is both free and Open Source. If that doesn't suit you, our users have ranked more than 50 alternatives to Cubase and 18 is open source so hopefully you can find a suitable replacement. Other interesting open source alternatives to Cubase are Ardour (Freemium, Open Source), Rosegarden (Free, Open Source), FamiStudio (Free, Open Source) and Qtractor (Free, Open Source).
Ardour is a hard disk recorder and digital audio workstation application. It runs on GNU/Linux, Mac OS X, and Windows. Ardour's intention is to provide digital audio workstation software suitable for professional use.
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Ardour vs Cubase opinions
Most users think Ardour is a great alternative to Cubase.
Opensource, available on Windows, Mac, and Linux, you can import PT projects, create your own model, and use it as a completed DAW for your computer.
FamiStudio is very simple music editor for the Nintendo Entertainment System or Famicom. It is designed to be easier to use than FamiTracker, but its feature set is also much more limited. It is targeted at both chiptune artists and NES homebrewers.
Bosca Ceoil is all about looping, and designed that way at its heart. Songs are built up from lots of tiny 16 note patterns – the intended workflow is that you loop over these single patterns until you have something you like, then you start making variations.