SlickRun is described as 'Free floating command line utility for Windows. SlickRun gives almost instant access to any program or website. SlickRun allows you to create command aliases (known as MagicWords), so C:\Program Files\Outlook Express\msimn.exe becomes MAIL' and is a application launcher in the os & utilities category. There are more than 25 alternatives to SlickRun for a variety of platforms, including Windows, Linux, File Explorer, Mac and Chocolatey apps. The best SlickRun alternative is Flow Launcher, which is both free and Open Source. Other great apps like SlickRun are Listary, Keypirinha, Executor and Find And Run Robot.
SlickRun is a GUI wrapping a command-line utility that effectively creates and uses shortcuts. OpenWith Enhanced is an add-on to the Open With command which shares nothing in common.