Marvin suite is a chemically intelligent desktop toolkit built to help you draw, edit, publish, render, import and export your chemical structures and as well as allowing you to convert between various chemical and graphical file formats.
BKChem is a free (as in free software :o) chemical drawing program. It was conceived and written by Beda Kosata and is currently maintained by Reinis Danne.
The last release was in 2010.
ACD/ChemSketch is a chemically intelligent drawing interface that allows you to draw almost any chemical structure including organics, organometallics, polymers, and Markush structures. Use it to produce professional looking structures and diagrams for reports and publications.This app doesn't have any features at the moment.
XDrawChem is a free software program for drawing chemical structural formulas, available for Unix and Mac OS. It is distributed under the GNU GPL. In Microsoft Windows this program is called WinDrawChem.This app doesn't have any features at the moment.Discontinued
Last release (1.10.2-1) was in January 2017.
If you are looking for a chemical sketcher or an alternative to your current chemical drawing application, there is no better choice than ChemDoodle. ChemDoodle works on all operating systems (both 32 and 64 bit), has one of the largest feature sets in the industry, has the most...This app doesn't have any features at the moment.
A 2D molecular editing tool for GNU/Linux, Mac OS X and Windows. Its goal is to help you draw molecules quick and easily. Of course your creations can be exported afterwards in high quality in a number of vector and bitmap formats.