PyREbox is described as 'Cisco Talos's PyREbox is a python QEMU-based sandbox environment designed to aid in reverse engineering. It can be used for security researchers to aid them in malware analysis, or for general developers with debugging their applications' and is an app in the Development category. There are seven alternatives to PyREbox for a variety of platforms, including Online / Web-based, Windows, Linux, Mac and Android. The best alternative is Cuckoo Sandbox, which is both free and Open Source. Other great apps like PyREbox are Any.Run (Freemium), FAME Automates Malware Evaluation (Free, Open Source), ANLYZ REVERSS (Free) and VMRay Analyzer Platform (Paid).
FAME is a recursive acronym meaning “FAME Automates Malware Evaluation”. It is meant to facilitate analysis of malicious files, leveraging as much knowledge as possible in order to speed up and automate end-to-end analysis.
REVERSS can analyze executables, URLs and PCAP files. It also show statistical data about found infections and the affected countries, etc. You can send the samples anonymously or logged in with Google to scan it privately.