PlayOnLinux - PlayOnMac is described as 'PlayOnLinux is a graphical frontend for the Wine software compatibility layer which allows Linux and Mac users to install Windows-based video games, Microsoft Office (2000 to 2010), Microsoft Internet Explorer, as well as many other applications' and is a very popular compatibility layer tool in the gaming software category. There are more than 25 alternatives to PlayOnLinux - PlayOnMac for a variety of platforms, including Linux, Mac, Windows, Wine and Android. The best alternative is Wine, which is both free and Open Source. Other great apps like PlayOnLinux - PlayOnMac are Lutris, RetroArch, Proton and GameHub.
Wine is a free, open source application for running Windows software on operating systems that are normally not supported. With Wine, you can install and run these applications just like you would in Windows.
Most users think Wine is a great alternative to PlayOnLinux - PlayOnMac.
Pegasus is a graphical frontend for browsing your game library (especially retro games) and launching them from one place. It's focusing on customizability, cross platform support (including embedded devices) and high performance.
The Windows Subsystem for Linux (WSL) is a new Windows 10 feature that enables you to run native Linux command-line tools directly on Windows, alongside your traditional Windows desktop and modern store apps.