The best App Store alternative to Homebrew is Ninite, which is free. If that doesn't suit you, our users have ranked more than 50 alternatives to Homebrew and 12 are App Stores so hopefully you can find a suitable replacement. Other interesting App Store alternatives to Homebrew are Flathub, GNOME Software, Arch User Repository (AUR) and Bazaar App Store.
Ninite is the easiest way to install software. Pick the apps you want, and the Ninite installer will download and install all of your selected apps at once, automatically. It is 100% hands-free; Ninite automatically rejects browser toolbars and other prepackaged junk.
Flathub is the place to get and distribute apps for all of desktop Linux. It is powered by Flatpak, allowing Flathub apps to run on almost any Linux distribution.
The Arch User Repository (AUR) provides user-made PKGBUILD scripts for packages not included in official repositories. These PKGBUILD scripts simplify building from source by explicitly listing and checking for dependencies and configuring the install to match the Arch...
Bazaar is a new app store for GNOME with a focus on discovering and installing applications and add-ons from Flatpak remotes, particularly Flathub. It emphasizes supporting the developers who make the Linux desktop possible.
Utility for KDE's Plasma desktop environment for browsing, installing, and removing applications, implemented as an app store like application.
A simple command line interface for the Mac App Store. Designed for scripting and automation.
Setapp provides a curated collection of commercial apps available through a low-cost subscription. Access to the apps is driven by a straight-forward local app that neatly organizes them in a searchable, filterable and configurable list.
Homebrew is for open source packages. Setapp is just a subscription-based app ownership platform for proprietary applications.
AppCenter is a fast software store built on top of libappstore (https://launchpad.net/libappstore)
It will help you install Flatpak apps in a user-friendly way. We have recipes for some of them to install them even better.
AUR-inspired database, and package manager to install, update (for real) and manage ALL AppImages and other portable formats for GNU/Linux, system-wide or locally, with the ease of APT and the power of PacMan.
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Ninite won't give you access to hundreds of open source and CLI softwares like Homebrew does.