Qt is a cross-platform application framework that is widely used for developing application software that can be run on various software and hardware platforms with little or no change in the underlying codebase, while having the power and speed of native applications.
wxWidgets is a C++ library that lets developers create applications for Windows, OS X, Linux and UNIX on 32-bit and 64-bit architectures as well as several mobile platforms including Windows Mobile, iPhone SDK and embedded GTK+.
Uno is the platform for building native mobile, desktop and WebAssembly apps with C#, XAML from single codebase. It's a Universal Windows Platform Bridge that allows UWP-based code (C# and XAML) to run on iOS, Android, and WebAssembly.
Avalonia is a WPF-inspired cross-platform XAML-based UI framework providing a flexible styling system and supporting a wide range of OSs: Windows (.NET Framework, .NET Core), Linux (GTK), MacOS, Android and iOS.
MauiKit is a framework based on QQC2 and Kirigami, that helps to create convergent applications that run on GNU Linux and Android, based on the Maui HIG. MauiKit is an open source framework to make the applications look good, made by .
The PySide project provides LGPL-licensed Python bindings for the Qt cross-platform application and UI framework. PySide Qt bindings allow both free open source and proprietary software development and ultimately aim to support all of the platforms as Qt itself.