Claude Fable 5 cuts biology false positives by 85 percent after safeguards update

Claude Fable 5’s updated biology safeguards now reduce biology-related false positives and fallbacks by about 85%.

Users can access a wider range of health, educational, and some clinical biology queries without triggering a fallback to a less capable model.

Requests involving dual-use research topics still prompt a switch to Opus 5 for safety.