ProtonUp-Qt Alternatives
ProtonUp-Qt is described as 'Install and manage GE-Proton, Luxtorpeda & more for Steam and Wine-GE & more for Lutris with this graphical user interface' and is a compatibility layer tool in the development category. There are more than 25 alternatives to ProtonUp-Qt for a variety of platforms, including Linux, Mac, Wine, Flathub and Windows apps. The best ProtonUp-Qt alternative is Wine, which is both free and Open Source. Other great apps like ProtonUp-Qt are WinBoat, Proton, Bottles and PlayOnLinux - PlayOnMac.
Alternatives list
Compatibility layer enabling Windows games on Linux via Steam Play, featuring advanced video playback, FSR integration, Nvidia CUDA support, raw input, per-game fixes automation, upstream Wine patches, frequent updates, wine-staging patches, and open-source maintenance.
35 WineBottler alternativesWineBottler is an App to manage and wrap your Windows apps into convenient OS X apps. WineBottler helps you with running Windows programs on OS X.
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A Vulkan-based translation layer for D3D9, D3D10 and D3D11, which can be used on Linux with Wine.
Steam emulator that emulates steam online features. Lets you play games that use the steam multiplayer APIs on a LAN without steam or an internet connection.
Phoenicis is a graphical front-end for Wine, a tool to help Linux and Mac users run games and programs for Windows. The future of PlayOnLinux and PlayOnMac.
Q4Wine is a qt4 GUI for wine that will help you manage wine prefixes and installed applications
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WineZGUI (pronounced Wine-Zee-Goo-Eee) is a wine frontend for playing windows games with wine easily. It is a collection of Bash scripts for Wine Prefix Management and Linux Desktop Integration for easier wine gaming experience using Zenity.
MiceWine is a project that aims to run Windows applications and games on Android smartphones.
Using Wineskin technology, Porting Kit is a PaulTheTall.com app that can install games and apps compiled for Microsoft Windows® in Mac OS X. It has access to a server where we store WSI files for more than 300 games, which can be installed by any Porting Kit user.
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