Project64 is not available for Mac but there are some alternatives that runs on macOS with similar functionality. The best Mac alternative is RetroArch, which is both free and Open Source. If that doesn't suit you, our users have ranked more than 10 alternatives to Project64 and six of them are available for Mac so hopefully you can find a suitable replacement. Other interesting Mac alternatives to Project64 are Mupen64Plus (Free, Open Source), Nostlan (Free, Open Source), MESS (Free Personal) and Sixtyforce (Freemium).
What is RetroArch? RetroArch is a modular multi-system emulator system that is designed to be fast, lightweight, and portable. It has features lacking in some emulators frontends, such as real-time rewinding and game-aware shading. What systems does it play?
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Most users think RetroArch is a great alternative to Project64.
A front-end or user interface (UI) is the presentation and interaction layer of an app or website. Most modern emulator apps have basic game list UIs that you can interact with using a mouse/keyboard but not a game controller.
MESS emulates portable and console gaming systems, computer platforms and calculators. The project strives for accuracy and portability and therefore is not always the fastest emulator for any one particular system.