There are many alternatives to PlayOnLinux for Mac if you are looking for a replacement. The best Mac alternative is Wine, which is both free and Open Source. If that doesn't suit you, our users have ranked more than 25 alternatives to PlayOnLinux and 16 are available for Mac so hopefully you can find a suitable replacement. Other interesting Mac alternatives to PlayOnLinux are RetroArch (Free, Open Source), Proton (Free, Open Source), CrossOver (Paid) and Pegasus (Free, Open Source).
Wine is a free, open source application for running Windows software on operating systems that are normally not supported. With Wine, you can install and run these applications just like you would in Windows.
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Most users think Wine is a great alternative to PlayOnLinux.
What is RetroArch? RetroArch is a modular multi-system emulator system that is designed to be fast, lightweight, and portable. It has features lacking in some emulators frontends, such as real-time rewinding and game-aware shading. What systems does it play?
Pegasus is a graphical frontend for browsing your game library (especially retro games) and launching them from one place. It's focusing on customizability, cross platform support (including embedded devices) and high performance.
A front-end or user interface (UI) is the presentation and interaction layer of an app or website. Most modern emulator apps have basic game list UIs that you can interact with using a mouse/keyboard but not a game controller.
Wineskin is a tool used to make ports of Windows software to Mac OS X. The ports are in the form of normal Mac application bundle wrappers. It works like a wrapper around the Windows software, and you can share just the wrappers if you choose. Best of all, its free!