Numba is described as 'gives you the power to speed up your applications with high performance functions written directly in Python' and is an app in the Development category. There are three alternatives to Numba for Linux, Mac and Windows. The best alternative is Cython, which is both free and Open Source. Other great apps like Numba are Shed Skin (Free, Open Source) and Berp (Free).
Cython is a language that makes writing C extensions for the Python language as easy as Python itself. Cython is based on the well-known Pyrex, but supports more cutting edge functionality and optimizations.
Shed Skin is an experimental compiler, that can translate pure, but implicitly statically typed Python (2.4-2.6) programs into optimized C++. It can generate stand-alone programs or extension modules that can be imported and used in larger Python programs.
Berp is an implementation of Python 3. At its heart is a translator, which takes Python code as input and generates Haskell code as output. The Haskell code is fed into a Haskell compiler (GHC) for compilation to machine code or interpretation as byte code.