Mesen is described as 'Multi-system emulator (NES, SNES, Game Boy, PC Engine, Master System/Game Gear) for Windows, Linux and macOS built in C++ and C#' and is a Game Emulator in the gaming software category. There are more than 10 alternatives to Mesen for a variety of platforms, including Windows, Linux, Android, Web-based and Mac apps. The best Mesen alternative is FCEUX, which is both free and Open Source. Other great apps like Mesen are jgenesis, Nestopia, Nestopia UE (Undead Edition) and ClownMDEmu.
FCEUX is a Nintendo Entertainment System (NES), Famicom, and Famicom Disk System (FDS) emulator. It supports both PAL (European) and NTSC (USA/JPN) modes. It supports both Windows and SDL versions for cross compatibility.
Nestopia is a NES emulator that was written in C++ and it is perfect for games requiring precise timing since it is very cycle-accurate. With support for an incredible amount of mappers. It also supports NSFs, the famicom disk system, save states, IPS patching, battery-saved...
Nestopia is a portable NES/Famicom emulator written in C++. Nestopia UE (Undead Edition) is a fork of the original source code, with enhancements from members of the emulation community.
Sega Mega Drive/Genesis and Sega CD emulator. It is designed as a modular project, consisting of a portable emulation core written in C and a feature-rich standalone frontend built with C++, SDL3, and Dear ImGui. You can try ClownMDEmu in your web browser at clownmdemu.clownacy.com.
NostalgiaNes is a high quality emulator based on the most up-to-date revision of the famous FCEUX.
PuNES is a high accuracy NES emulator.
In addition to the standard color pallettes used by most NES emulators, PuNES uses a color palette derived from an actual tv.
I like puNES because it's the most accurate Nes/Famicom/FDS/Vs.System/Playchoice-10 Emulator, with the most mappers support, ease of use GUI, supports shaders.
Nesbox Emulator is a multiplatform emulator of video consoles. You can play your favorite NES, Super Nintendo, Sega Genesis and GameBoy Color/Advanced games on any computer working under Windows 8.1/RT/Phone or directly in the browser.
MESS emulates portable and console gaming systems, computer platforms and calculators. The project strives for accuracy and portability and therefore is not always the fastest emulator for any one particular system.
NES emulator for Android phones.
This project is based on sources, published by original Nesoid developer, who in turn used code of GPFCE, forked from FCEUltra, currently incarnation of which is known as FCEUX.
DroidEmu is a game system to play SNES, NES, GameBoy Advanced, GameBoy/Color, SEGA GameGear, SEGA Genesis games on your Android phone. It runs thousands of games at full speed.
Jnes is a NES emulator for win32 platforms that uses DirectX for its hardware interface. Its emulation capabilities include graphics, sound, input devices, and emulating quite a few memory mapping boards found in most USA games and a few popular japanese ones.
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It's been a while since FCEUX was the most preferred emulator among rom hacking communities, the tools built-in are solids, taking ram search for relative searching as example.