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Xcalibur Alternatives

Xcalibur is described as 'software provides method setup, data acquisition, data processing, and reporting. It provides complete security and tracking, and compliant reporting—it supports 21-CFR part 11—if used with XReport' and is an app. There are seven alternatives to Xcalibur for Windows, Linux and Mac. The best alternative is OpenChrom, which is both free and Open Source. Other great apps like Xcalibur are Chromeleon, Clarity, ChemStation and Empower.

This page was last updated May 8, 2019
  • Windows

Xcalibur software provides method setup, data acquisition, data processing, and reporting. It provides complete security...

Learn more about Xcalibur

  1. OpenChrom

    • FreeOpen Source
    • Mac
    • Windows
    • Linux

    OpenChrom is a data analysis tool for gas chromatography and mass spectrometry. Its functionality and algorithms can be extended using a flexible plugin approach. File formats from various vendors are supported.

    OpenChrom vs Xcalibur opinions
    pros, cons and recent comments

    OpenChrom is for GC-MS, Xcalibur does LC-MS data analysis

    Negative comment about 3 years ago
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  2. Chromeleon

    • Windows

    Multi-vendor instrument control that supports Mass Spectrometer (MS) instrument control and data processing with all main front-end separation techniques (LC, GC, IC) in an enterprise environment.

  3. Clarity

    • Windows

    Chromatography Data Station (CDS) with optional software modules for data acquisition, processing and instrument control

  4. ChemStation

    • Windows

    Legacy control and data analysis software for Agilent GC/MSD.


    superseded by MassHunter, but put here for reference as many labs still use it

    No screenshots yet
  5. Empower

    • Windows

    Controls chromatography instruments and processes data.

  6. Analyst

    • Windows

    Mass spectrometry software for data acquisition of large and small molecules in both regulated and non-regulated environments. The software is designed to be used with any SCIEX QTRAP, triple quadrupole, or TripleTOF LC/MS/MS System.

    No screenshots yet
  7. MassHunter

    • Windows

    Instrument control, data acquisition, qualitative and quantitative data analysis, and reporting for Agilent time-of-flight (TOF), quadrupole time-of-flight (Q-TOF), ICP-MS, and triple quadrupole systems.

Showing 7 of 7 alternatives