Vvvv is not available for Mac but there are plenty of alternatives that runs on macOS with similar functionality. The best Mac alternative is Processing, which is both free and Open Source. If that doesn't suit you, our users have ranked more than 10 alternatives to Vvvv and 16 are available for Mac so hopefully you can find a suitable replacement. Other interesting Mac alternatives to Vvvv are Pure Data (Free, Open Source), Isadora (Paid), Cinder (Free, Open Source) and Vuo (Free Personal, Open Source).
Processing is an open source programming environment and library built to handle images, animation, and interactivity. It is used by students, artists, designers, researchers, and hobbyists for learning to code, prototyping, and producing full applications.
Pd (aka Pure Data) is a real-time graphical programming environment for audio, video, and graphical processing. It is the third major branch of the family of patcher programming languages known as Max (Max/FTS, ISPW Max, Max/MSP, jMax, etc.
VDMX5 was created from the ground up to meet the demands of realtime video performance. Built around a robust data processing architecture it was designed to be used with whatever hardware- or software- you've got available.