TubeCast has been discontinued. Similar apps include Free YouTube Uploader, which is free. Other options are YouTube Bulk Uploader for the Lazy and PHP Youtube Uploader. In total there are three apps like TubeCast for Windows and self-hosting.
Free YouTube Uploader is the first PC desktop application to upload video to YouTube without using the original YouTube web interface. If you often upload videos, this program will be a good companion for you as it supports batch mode upload.
United Kingdom
YouTube Bulk Uploader for the Lazy allows you to easily BULK UPLOAD and TAG 1000's of videos OFFLINE! The software provides bulk editing of videos Tags, Categories, Titles etc and provides a simple to use interface for uploading and managing videos.
United States
Upload videos to Youtube via PHP on your server.
In general case you upload your videos via the Flash Uploader of Youtube. That might be a good way sometimes, but if you do this very often, interruptions of the upload may occur. It should be your decision how to upload those gig.
Germany
EU