Pyramid is described as 'open source web framework written in Python and is based on WSGI. It minimalistic web framework inspired by Zope, Pylons and Django. When You Need Pyramid' and is an app in the Development category. There are more than 25 alternatives to Pyramid for a variety of platforms, including Mac, Linux, Windows, Online / Web-based and Self-Hosted solutions. The best alternative is Node.js, which is both free and Open Source. Other great apps like Pyramid are Django (Free, Open Source), Flask (Free, Open Source), Ruby on Rails (Free, Open Source) and Symfony (Free, Open Source).
Django is a high-level Python Web framework that encourages rapid development and clean, pragmatic design. Built by experienced developers, it takes care of much of the hassle of Web development, so you can focus on writing your app without needing to reinvent the wheel.
Web2py is an open source web application framework. Web2py is written in the Python language and is programmable in Python. Since web2py was originally designed as a teaching tool with emphasis on ease of use and deployment, it does not have any project-level configuration files
Play is a web application framework, written in Scala and Java, which follows the model–view–controller (MVC) architectural pattern. The Play framework makes it easier to build web applications with Java & Scala.