The best Graphic Design alternative to OpenToonz is Pencil2D, which is both free and Open Source. If that doesn't suit you, our users have ranked more than 25 alternatives to OpenToonz and six of them are Graphic Design Tools so hopefully you can find a suitable replacement. Other interesting Graphic Design Tool alternatives to OpenToonz are enve, Storyboarder, Toon Boom Harmony and TVPaint Animation.
Pencil2D is an opensource animation/drawing software for Mac OS X, Windows, and Linux, based on old Pencil software. It lets you create traditional hand-drawn animation (cartoon) using both bitmap and vector graphics.
Enve is a free and open-source 2D animation app. It can create both vector and raster animations and even use sound and video files. It has been created with flexibility and expandability in mind.
Storyboarder makes it easy to visualize a story as fast you can draw stick figures. Quickly draw to test if a story idea works. Create and show animatics to others. Express your story idea without making a movie.
Toon Boom Harmony Network is the industrial animation software for studios worldwide.
TVP Animation is the leading paperless drawing and animation tool, able to imitate traditional techniques such as Pen Brush, Gouache, Watercolour, Pencil, Felt-tip and Airbrush, and animate them over frames.
Artist Code is an intuitive software for creating animation ( Movie, Animated Gif, Images) only by coding, it allows you to add image, text and pixels and place them with simple script offering you a fun and unlimited way to create whatever you want.
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One of the only professionally used software available for linux. It's also a bit of an industry standard, even though Toon Boom Harmony seems to be taking over.