Natural Selection is described as '2 is a RTS/Shooter/Biter that you either play as marines or aliens, it is currently under development by Unknown Worlds' and is a first-person shooter in the games category. There are more than 10 games similar to Natural Selection for a variety of platforms, including Windows, Mac, Linux, Xbox and Playstation apps. The best Natural Selection alternative is Doom. It's not free, so if you're looking for a free alternative, you could try Tremulous or Unvanquished. Other Natural Selection like games are Prodeus, Dead Space, Shadow Warrior (Reboot) and Aliens vs Predator.
Doom is a science fiction horror-themed first-person shooter video game in which players assume the role of a space marine, popularly known as "Doomguy", who must fight his way through the hordes of invading demons from Hell.
Prodeus is a first-person shooter of old, re-imagined using modern rendering techniques and technology. Experience the quality you’d expect from a modern AAA game, designed with retro aesthetics and gameplay that invoke the tech-imposed limits of older hardware.
Dead Space is a survival horror third-person shooter video game for Microsoft Windows, PlayStation 3 and Xbox 360.
Shadow Warrior is a series of first-person shooter video games that focuses on the exploits of Lo Wang, a modern ninja warrior who fights through hordes of demons.
Tremulous is a free, open source game that blends a team based FPS with elements of an RTS. Players can choose from 2 unique races, aliens and humans. Players on both teams are able to build working structures in-game like an RTS.
Unvanquished is a free, open-source first-person shooter combining real-time strategy elements with a futuristic, sci-fi setting. It is available for Windows, Linux, and Mac OS X.
Aliens vs. Predator is a science fiction first-person shooter video game, developed by Rebellion Developments
Zandronum is a multiplayer oriented port, based off Skulltag, for Doom and Doom II by id Software.
Battle through an onslaught of mystical backwater cultists, possessed militants & even darker forces as you attempt to discover just what lurks beneath the Earth in this retro FPS inspired by the '90s legends.
Wrack: Exoverse is the follow-up to the 2014 first-person shooter Wrack. It was a very fast-paced, arcade-style game with heavy influences from classic shooters like Doom and Quake.
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The Core Element that makes Natural Selection 2 Unique is the RTS part that is not existing in Doom. Also Doom is a more known for its sigle player experience while NS2 is Multiplayer only