Covexe

Covexe (Covexe Labs) is free, browser-based software for running systematic reviews and meta-analyses from start to finish, with nothing to install. It brings the whole evidence-synthesis workflow into one workspace and adds an AI co-pilot that helps with the slow, manual steps.

Review workflow:

• Import references from PubMed, Rayyan, Covidence, EndNote, Zotero, and RevMan (RIS, .nbib, BibTeX, PubMed XML, CSV, Excel), with automatic duplicate detection.
• Define the research question, protocol, and PICO framework.
• AI-assisted title/abstract and full-text screening with relevance scoring and transparent include/exclude reasons.
• Live PRISMA 2020 flow diagrams that update as you screen.
• Structured data extraction and a study characteristics (Table 1) summary.

Analysis and appraisal:

• Pairwise (comparative) meta-analysis with forest plots.
• Prevalence / proportion meta-analysis.
• Network meta-analysis (NMA) with a network map.
• Risk-of-bias assessment (RoB 2) and GRADE certainty ratings.
• Leave-one-out and sensitivity analyses.

Covexe supports systematic reviews, scoping reviews, and umbrella reviews, and runs entirely in the browser so teams can work with no downloads or local installs. Core tools are free.

It is designed as an alternative to systematic review and meta-analysis tools such as Covidence, Rayyan, DistillerSR, and Review Manager (RevMan), combining screening, extraction, meta-analysis, and reporting in one place.