Comix Zone is described as 'Classic, comic-themed arcade beat 'em up from SEGA past'. There are three games similar to Comix Zone for Android, Android Tablet, iPad and iPhone. The best alternative is Altered Beast, which is free. Other Comix Zone like games are Ghosts'n Goblins (Paid) and Ghouls'n Ghosts (Paid).
A legend among videogames, Ghosts'n Goblins is the definitive sidescrolling platformer where you combat ghouls and other deadly creatures of the night. It's been remade for modern devices for your mobile enjoyment.