Bottle is described as 'fast, simple and lightweight WSGI micro web-framework for Python. It is distributed as a single file module and has no dependencies other than the Python Standard Library' and is an app in the Development category. There are six alternatives to Bottle for a variety of platforms, including Mac, Windows, Linux, Self-Hosted solutions and Python. The best alternative is Django, which is both free and Open Source. Other great apps like Bottle are Flask (Free, Open Source), FastAPI (Free, Open Source), Falcon framework (Free, Open Source) and jam-py (Free, Open Source).
Django is a high-level Python Web framework that encourages rapid development and clean, pragmatic design. Built by experienced developers, it takes care of much of the hassle of Web development, so you can focus on writing your app without needing to reinvent the wheel.
Falcon is a bare-metal Python web API framework for building very fast app backends and microservices. Organizations like LinkedIn, Leadpages, Wargaming, and Rackspace rely on Falcon for critical projects.
The jam.py is an object-oriented, event-driven framework with hierarchical structure. All this, in combination with very tight DB/GUI coupling, is the base for the DRY (don't repeat yourself) principle that is underlying the framework.