Spine is described as 'Is 2D animation software designed specifically for software and game development. Animators, artists and programmers unite to bring your games alive' and is a Animation Maker in the development category. There are more than 10 alternatives to Spine for a variety of platforms, including Windows, Mac, Linux, Web-based and Flathub apps. The best Spine alternative is Synfig Studio, which is both free and Open Source. Other great apps like Spine are Inochi Creator, enve, Expressive Animator and AnimeEffects.
Open-source 2D software for creating animations with vector and bitmap artwork, advanced bone rigging, tweening, timeline editing, onion skinning, multi-layer effects, audio sync, and multi-format rendering on Windows, Linux, and macOS.
you can't get it into games and it isn't a runtime
Synfig isn't bone-based 2D animation
Inochi creator is a framework for realtime 2D puppet animation. On this site you can find the reference implementation as well as the official tooling for creating and using Inochi2D puppets for VTubing.
Enve is a free and open-source 2D animation app. It can create both vector and raster animations and even use sound and video files. It has been created with flexibility and expandability in mind.
Create interactive SVG animations with precise keyframe and easing control, custom vector paths, shape and text editing, gradients, masks, boolean operations, blend modes, snap, grid, advanced export options including Lottie, GIF, and no JavaScript required.
AnimeEffects is a 2D keyframe animation tool based on deformation of polygon meshes. You can easily operate, quickly shape your idea, and remake at any time if you have changed your mind.
Live2D is the world's first drawing technology to enable 3D rendering of 2D images. This technology supports a variety of portable consoles and smartphones, and Live2D is already being utilized for games that take advantage of the unique characteristics of hand drawn artwork.
Marionette Studio is a great software, powerful, easy and very intuitive to create 2D animations, characters for video games and more.
Spriter : an intuitive 2D animation tool for video game makers.
Spriter enables the “modular” method of animating where, instead of each frame being a single complete image, it is constructed from many small, re- useable images (such as body parts). Each of these images that ar.
Far more affordable, however lacking in mesh functions.
This software is used to create fluid and natural animation to 2D graphics, easily allowing the user to use secondary animation to make it look more natural.
E-mote is an engine which can create smooth and stereoscopic animation in a few steps from the character's 2D illustration. You can easily and dynamically move the expressions, orientations, limbs of standing pictures characters and make it look 3D.
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You can't make game animations in Synfig Studio, only animation clips and animation movies