OpenBio

Predict protein structures, design molecules, and analyze biological data using Boltz-2, ProteinMPNN, GeoDock and 150+ tools. No coding required. Chat-first Interface for Research and Daily Workflows. Upload, browse, and manage research files instantly. Drag-and-drop support for PDB, FASTA, SMILES, CSV, and papers. Interactive workspace for analyzing structures and data. From protein structures to tables. Ask questions in natural language. Run predictions and analyze data. No command line needed. Upload your data after you've finished your experiment and let OpenBio analyze it. Get structure visualizations, composition data, and intelligent next-step suggestions. Connect to external tools and services via Model Context Protocol. connect with biorender, synpase, scholar gateway, and more. Import and manage citations directly from Zotero. Access your research library, sync references, and cite papers with Zotero. Create your own MCP servers. Use your own data and tools to create custom workflows. No coding required. Access structure prediction models (Boltz-2, Chai-1, ProteinMPNN), biological databases (PDB, UniProt, ChEMBL, PubMed), and DNA assembly tools. Predict structures with Boltz-2 and Chai-1. Design proteins with ProteinMPNN. Optimize stability with ThermoMPNN. Calculate molecular properties with RDKit. Search ChEMBL for bioactivity. Identify drug-like compounds and bioisosteres. Design PCR primers automatically. Visualize restriction maps and gel results. Upload proteins, DNA, compounds, or papers. OpenBio analyzes content automatically. Get structure visualizations, composition data, and intelligent next-step suggestions. Search PDB structures, UniProt sequences, and AlphaFold predictions in one place. Natural language queries work instantly. Access gene info from MyGene, genetic variants from MyVariant, and disease data from MyDisease. Unified genomics search. Search PubMed papers, arXiv preprints, and web sources. Find relevant research with AI-powered summaries. Organize research in structured projects. Upload datasets and track results. Digital notebooks capture findings automatically.