Native Instruments Guitar Rig is a truly legendary guitar suite for PC and Mac. With intricately modeled sound that's hard to match, it's amazing there would be so many outstanding alternatives. Those alternatives span all major platforms, most commonly Mac and Windows. Linux suites are generally open-source.
Electrum is the all-in-one single-screen guitar solution. The last amplifier and pedalboard your guitar will ever need. It matches any guitar style or technique. Rhythm guitar or solo. From jazz to modern metal.
Axiom is an effects processor and amp simulation for guitar and bass that includes 44 built-in effects that can be loaded in any of the 32 plug-in slots, including a built-in version of Late Replies for creative delays and reverbs, and a built-in version of Destructor to add...
Master FX contains set of classic sound effects which you can use for guitar, synth or voice at live performance or for processing tracks in DAW and other mixing apps thru Inter-App Audio or with Audiobus.
TH-U offers a massive suite of high-quality guitar amps and effects, the world's largest collection of models in a single software. Expanding on the design of the original TH3 suite, TH-U features 239 models and a huge list of advanced capabilities.
BIAS FX is a world-class, guitar amp-and-effects processor for desktop and iPad use. It gives you an endless collection of insanely great-sounding guitar pedalboards, ultra-high definition stereo rack effects, dual amps and dual signal chain.