ACD/ChemSketch is not available for Mac but there are some alternatives that runs on macOS with similar functionality. The best open source Mac alternative is Avogadro. If that doesn't suit you, our users have ranked more than 10 alternatives to ACD/ChemSketch and five of them are open source and available for Mac so hopefully you can find a suitable replacement. Other interesting open source Mac alternatives to ACD/ChemSketch are JChemPaint, BKchem, MollyCule and XDrawChem.
Avogadro is an advanced molecule editor and visualizer designed for cross-platform use in computational chemistry, molecular modeling, bioinformatics, materials science, and related areas.
JChemPaint (or JCP for short here) is the editor and viewer for 2D chemical structures developed using the Chemistry Development Kit (CDK).
BKChem is a free (as in free software :o) chemical drawing program. It was conceived and written by Beda Kosata and is currently maintained by Reinis Danne.
MollyCule is a completely free Open Source Chemistry visualisation program for MacOS, Linux and Windows. MollyCule is designed to be a nice, easy to use program to help ordinary people who want to explore Chemistry.
XDrawChem is a free software program for drawing chemical structural formulas, available for Unix and Mac OS. It is distributed under the GNU GPL. In Microsoft Windows this program is called WinDrawChem.
United States
Czechia
EU
