TurboGears is described as '2 is built on top of the experience of several next generation web frameworks including TurboGears 1 (of course), Django, and Rails' and is an app in the Development category. There are more than 10 alternatives to TurboGears for a variety of platforms, including Mac, Windows, Linux, Self-Hosted solutions and Python. The best alternative is Node.js, which is both free and Open Source. Other great apps like TurboGears are Django (Free, Open Source), Flask (Free, Open Source), Ruby on Rails (Free, Open Source) and CodeIgniter (Free, Open Source).
Django is a high-level Python Web framework that encourages rapid development and clean, pragmatic design. Built by experienced developers, it takes care of much of the hassle of Web development, so you can focus on writing your app without needing to reinvent the wheel.
Web2py is an open source web application framework. Web2py is written in the Python language and is programmable in Python. Since web2py was originally designed as a teaching tool with emphasis on ease of use and deployment, it does not have any project-level configuration files
Falcon is a bare-metal Python web API framework for building very fast app backends and microservices. Organizations like LinkedIn, Leadpages, Wargaming, and Rackspace rely on Falcon for critical projects.