PowerGREP is not available for Mac but there are plenty of alternatives that runs on macOS with similar functionality. The best Mac alternative is DocFetcher, which is both free and Open Source. If that doesn't suit you, our users have ranked more than 50 alternatives to PowerGREP and 12 are available for Mac so hopefully you can find a suitable replacement. Other interesting Mac alternatives to PowerGREP are grep (Free, Open Source), The Silver Searcher (Free, Open Source), FAR - Find And Replace (Free, Open Source) and Find Any File (Paid).
DocFetcher is a portable German/English open source desktop search application. It allows you search the contents of documents on your computer. - You can think of it as Google for your local document repository.
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DocFetcher vs PowerGREP opinions
pros, cons and recent comments
cdokolas DocFetcher does not support regular expressions (regex) for text search
Regular expressions are a powerful tool for developers, but they aren't the easiest things to build and debug. Oyster helps you interactively build and test them, storing each "pearl" in an easy to access library.
Scherlokk is a lightning fast file search utility build for precise and reliable search of every file which meets the search criteria. Music, pictures, bookmarks, documents, etc can be found quickly and easily.
Rummage is a cross platform tool for crawling directories and searching and replacing in text files. It is written in Python and uses wxPython for the GUI. Rummage allows for literal or regex searches and has configurations for limiting the files etc.