There are many alternatives to PlayOnLinux for Mac if you are looking for a replacement. The best Mac alternative is Wine, which is both free and Open Source. If that doesn't suit you, our users have ranked more than 25 alternatives to PlayOnLinux and 16 are available for Mac so hopefully you can find a suitable replacement. Other interesting Mac alternatives to PlayOnLinux are RetroArch (Free, Open Source), Proton (Free, Open Source), CrossOver (Paid) and Pegasus (Free, Open Source).
Using Wineskin technology, Porting Kit is a PaulTheTall.com app that can install games and apps compiled for Microsoft Windows® in Mac OS X. It has access to a server where we store WSI files for more than 300 games, which can be installed by any Porting Kit user.
PyWinery is a graphical, easy and simple wine-prefix manager which allows you to launch apps, explore and manage configuration of separate prefixes, graphically and faster than setting variables on linux shell.
Direct3D 9 compatibility layer using Vulkan. The Goal of this project is to create a high performance Direct3D 9 implementation using a cross-platform graphics API. Represent entire series of VK9 games.
Run your Windows applications on OSX without the need of buying a Windows license. Well, you even do not need to install Windows. Just download WinOnX and you are ready to go within 2 minutes. No need to install Windows or a virtual machine.