There are many alternatives to PlayOnLinux for Linux if you are looking for a replacement. The best Linux alternative is Wine, which is both free and Open Source. If that doesn't suit you, our users have ranked more than 25 alternatives to PlayOnLinux and many of them are available for Linux so hopefully you can find a suitable replacement. Other interesting Linux alternatives to PlayOnLinux are Lutris (Free, Open Source), RetroArch (Free, Open Source), Proton (Free, Open Source) and GameHub (Free, Open Source).
Using bare wine and dosbox usually gives problems when launching a mixture of Windows and MS-Dos applications. Launching a Dos program on Wine sometimes fails, as Wine performs all kinds of custom configurations intended to use Dos programs in particular cases. Represent entire series of exeCute games.