There are many alternatives to PlayOnLinux for Linux if you are looking for a replacement. The best Linux alternative is Wine, which is both free and Open Source. If that doesn't suit you, our users have ranked more than 25 alternatives to PlayOnLinux and many of them are available for Linux so hopefully you can find a suitable replacement. Other interesting Linux alternatives to PlayOnLinux are Lutris (Free, Open Source), RetroArch (Free, Open Source), Proton (Free, Open Source) and GameHub (Free, Open Source).
Vineyard is a collection of tools and libraries designed to make managing Windows programs on Linux easier. More specifically, it aims to improve the integration of Wine and the Free Desktop and to make it easier to create programs and tools that integrate with Wine.
WinConn simplifies creation, management and desktop integration of remote windows applications in Ubuntu Linux. It uses RemoteApp technology, implemented by FreeRDP project to provide seamless user experience.
PyWinery is a graphical, easy and simple wine-prefix manager which allows you to launch apps, explore and manage configuration of separate prefixes, graphically and faster than setting variables on linux shell.
Direct3D 9 compatibility layer using Vulkan. The Goal of this project is to create a high performance Direct3D 9 implementation using a cross-platform graphics API. Represent entire series of VK9 games.