Microsoft Expression Blend is not available for Mac but there are a few alternatives that runs on macOS with similar functionality. The best Mac alternative is Microsoft Visual Studio. It's not free, so if you're looking for a free alternative, you could try React Studio or Cevelop. If that doesn't suit you, our users have ranked more than 10 alternatives to Microsoft Expression Blend and four of them are available for Mac so hopefully you can find a suitable replacement.
Microsoft Visual Studio is an integrated development environment (IDE) from Microsoft. It is used to develop computer programs for Microsoft Windows, as well as web sites, web applications and web services.
React Studio lets you create components either visually or in code, then use them interchangeably in your designs. Customize your components with advanced property UIs and dynamic previews in the editing canvas.
MaxBlox is a complete application development platform. The entire system is web-based and allows the ability to build applications that operate over the web. This is architected as a Platform as a Service (PaaS) system.