ComiPo is not available for Mac but there are some alternatives that runs on macOS with similar functionality. The best Mac alternative is Clip Studio Paint. It's not free, so if you're looking for a free alternative, you could try MediBang Paint or PixelStyle. If that doesn't suit you, our users have ranked nine alternatives to ComiPo and five of them are available for Mac so hopefully you can find a suitable replacement. Other interesting Mac alternatives to ComiPo are CorelDRAW Graphics Suite (Paid) and Artipic Photo Editor (Paid).
MediBang Paint is a lightweight software for illustration and making comic books on Windows and Mac OS. Features -You can save multiple pages in one file. -Perspective grids for easily drawing backgrounds or speed lines.
PixelStyle Photo Editor for Mac is an all-in-one photo editing and graphic design software, providing professional high-quality photo processing tools to edit the photos, enhance and touch up photos on Mac OS X.