If you are looking for a chemical sketcher or an alternative to your current chemical drawing application, there is no better choice than ChemDoodle. ChemDoodle works on all operating systems (both 32 and 64 bit), has one of the largest feature sets in the industry, has the most customizable graphics, pastes scalable vector graphics into Microsoft Office, iWork and OpenOffice (among others), and can read and write all of our competitors’ formats.
- Closest thing to ChemDraw functionality and, unlike ChemDraw, it works natively on Linux. Sadly, the author has chosen a frustrating atom-first drawing mechanic which is hugely counterintuitive. But if you can learn to accept it, ChemDoodle is a respectable ChemDraw alternative (unless you need to draw pi complexes).