New Twitter throwing you for a loop? Here are some clients that can help!

TweetDeck makes it easier for publishers, marketers, and power users to track the real-time conversations they care about. It brings more flexibility and insight to power users through a customizable layout that lets you keep up with the people and topics that matter most to you. Among its many functionalities, TweetDeck allows you to have multiple timelines, to manage several accounts, to follow hashtags, to only see tweets from a certain location… If you want to customize TweetDeck even more, you can also use the Better TweetDeck browser extension or use another app based on TweetDeck like TweetDuck, Tweetdeckr, or Tweeten.

Tweetbot is a Twitter client for macOS and iOS. Thanks to it, you can follow several threads at the same time, consult a timeline created from your lists, interact easily with your subscribers and subscriptions, or create tweets with photos or your geographical position.
Its simple and intuitive interface does not take regular features away with an almost identical operating mode and, as always, the possibility to rank your favorites, search for content, and consult the top tweets of your country.

Twidere is a free and open-source Twitter client that offers many customization options. Background color, tweets layout, card size, tab management, notifications… Nearly everything can be adjusted, up to and including the cache size and the number of tweets loaded at each refresh. You can also manage multiple accounts, use a night mode, enable powerful mute filters, send direct messages, and much more.

Twitterrific is an extremely complete Twitter client, offering many options associated with keyboard shortcuts. It was one of the first Twitter clients for macOS, but it has successfully been able to keep up against more recent Twitter apps in terms of features. Twitterrific allows you to post tweets, reply directly to messages, add photos or locations to your tweets, open links in a small integrated web browser, and more. An iOS version of the application is also available.

Plume, formerly Touiteur, is a beautiful and completely customizable Twitter app. It allows you to manage multiple accounts, mute users, words, or applications, share Tweets on Facebook, preview pictures in your timeline, answer to direct messages, and much more. The app also has an internal web browser to view links easily. Plume is only available for Android, so if you're an Apple user, you might want to use Tweetbot or Twitterrific instead.

If you're looking for a Twitter desktop application for your Linux operating system, especially a lightweight and simple program you can just leave running with very little drain on system resources, Birdie may be for you. While it may be very light and simple, it is also beautiful and designed very much to look and behave like elementary applications that you would see in elementary OS or arguably even like the latest Gnome applications.

Echofon is an easy to use, super-fast Twitter app for iOS and Android.
It's easy to do common Twitter tasks such as viewing your timeline, messages, replies, lists and favorites. Echofon has a powerful tweet-authoring tool where you can write tweets, take photos, record video, and update your current location. The Echofon interface was carefully designed to be comfortably left open all day. It stays out of the way when necessary and expands to support all the advanced features you need when you need them.

Choqok (which means “sparrow” in ancient Persian) is a free and open-source Twitter client designed for KDE Plasma that provides a wide range of features that will appeal to the most experienced users. It allows you to quickly publish a status message, update your profile, manage your favorites, send and receive private messages, manage your followers, and more.

Rainbow Stream is a free, open source, smart terminal based Twitter client released under the MIT License. It provides a real time tweet stream and allows you to compose, search, favorite, and much more directly from your Linux terminal. It is written in Python and built on top of the Twitter API and Python Twitter Tool. To run this application in your console, you must have installed Python and pip version 2.7.x or 3.x.