Apps with 'Run in existing prefix' feature
WineBottler is an App to manage and wrap your Windows apps into convenient OS X apps. WineBottler helps you with running Windows programs on OS X.
Discontinued
The application has not been updated for almost three years: https://bitbucket.org/winebottler/winebottler/src/master/, https://bitbucket.org/winebottler/winebottler/src/master/It also does not support the latest versions of macOS: https://www.reddit.com/r/winehq/comments/j43ziq/comment/g7gqpk5/