Apps with '2D and 3D physics' feature

Blender is the free and open-source 3D creation suite. It supports the entirety of the 3D pipeline—modeling, rigging, animation, simulation, rendering, compositing, video editing, and motion tracking.

GDevelop is an open-source game making software designed to be used by everyone. Any kind of 2D games can be created with it and no programming skills are required to get started. Logic of games are made using visual events.

Algodoo gives you the opportunity to play with physics. Use your own hands and simple drawing tools to design, construct and explore the world of physics.

Roblox allows you to create games, build whatever you want with lego-like bricks, play other games made by users of the community, and even participate in the economy by trading, selling, buying, and collecting items.

Garry's Mod is a Sandbox Game based around the idea of building. Unlike most other games there aren't any objectives - you can't lose and you definitely can't win.

BKChem is a free (as in free software :o) chemical drawing program. It was conceived and written by Beda Kosata and is currently maintained by Reinis Danne.

The Legend of Zelda: Mystery of Solarus DX is set to be a direct sequel to The Legend of Zelda: A Link to the Past on the SNES, using the same graphics and game mechanisms.

AppGameKit is a simple cross platform game development tool that runs on Windows, Linux, MacOS and Raspberry Pi. A version to run on Android and iOS is also available.

Tired of the roblox tyranny and greed? The Novetus community game is the solution!
Novetus was made to improve on RBXLegacy, with the addition of new features that enhance the
launcher for mod development, player customization, and overall usability.

HARFANG® 3D is a framework for 3D & 2D application development. It can manage & display complex 3D scenes, sound, music, access VR devices such as the HTC Vive, Oculus Rift, Lenovo Explorer.
HARFANG® is available for Python, Lua and C++ languages.

AppGameKit Studio is a fully featured cross-platform game development tool set that runs on Windows, Linux and MacOS.

AGKSharp is a free implementation of AppGameKit to be used with C# and .NET.

Artist3D is an extraordinarily easy-to-use 3D polygon modeling tool. It works completely without forms, pull-down menus, pop-up menus and text input.